Two-Stage Genome-Wide Search for Epistasis with Implementation to Recombinant Inbred Lines (RIL) Populations

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Two-Stage Genome-Wide Search for Epistasis with Implementation to Recombinant Inbred Lines (RIL) Populations

OBJECTIVE AND METHODS This paper proposes an inegrative two-stage genome-wide search for pairwise epistasis on expression quantitative trait loci (eQTL). The traits are clustered into multi-trait complexes that account for correlations between them that may result from common epistasis effects. The search is done by first screening for epistatic regions and then using dense markers within the i...

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Title : “ An efficient genome - wide multilocus epistasis search ”

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0115680